Biology and therapeutics
نویسندگان
چکیده
منابع مشابه
Chemical biology: probes and therapeutics
In the Chemical Biology Minisymposium, cochaired by Alice Ting and Lisa Belmont, the first three talks focused on the development of novel probes for cell biology, while the last three presentations highlighted inhibitors of proteins previously believed to be " undruggable. " Daniel Hochbaum (Cohen lab, Harvard University) described an optical probe for imaging single action potentials using th...
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The liver has a remarkable capacity to regenerate after injury. Recent work has demonstrated that repair may call upon either the division of pre-existing mature cells, or the expansion of intrahepatic progenitor cells. Furthermore, progenitors may migrate into the liver from the bone marrow. Understanding and exploiting the cell biology of the liver provides the basis for innovational treatmen...
متن کاملChemical Biology Screen for Prostate Cancer Therapeutics
Prostate cancer initially responds to hormone-based therapeutics such as anti-androgen treatment or chemotherapeutics but eventually becomes resistant. Novel treatment options are therefore urgently needed. This thesis study applied a high-throughput screen of 4910 known drugs and drug-like small molecules to identify compounds that selectively inhibit growth of prostate cancer cells. In additi...
متن کاملEpigenomics: From Chromatin Biology to Therapeutics
in order to encourage them to have some time and patience for the next science writer who knocks on their door. AA: That was my next question. Physicians and scientists usually have precious little free time for pleasure reading, let alone keeping up with scientific literature. How could they benefit from reading Spillover? Some concerns I heard were that there are too many details here that yo...
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Inorganic nitrate and nitrite from endogenous or dietary sources are metabolized in vivo to nitric oxide (NO) and other bioactive nitrogen oxides. The nitrate-nitrite-NO pathway is emerging as an important mediator of blood flow regulation, cell signaling, energetics and tissue responses to hypoxia. The latest advances in our understanding of the biochemistry, physiology and therapeutics of nit...
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ژورنال
عنوان ژورنال: The Dublin Journal of Medical Science
سال: 1907
ISSN: 0790-231X
DOI: 10.1007/bf02974337